Research Updates
Detemir and Degludec: Structure, Formulation, and Evidence
A review-based guide to detemir and degludec, separating structural modifications, release mechanisms and gaps in safety and clinical evidence.
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Research Updates
A place for future source-led coverage of new publications.
Research Updates
Oxytocin Research: Keep the Question Attached to the Result
Compare an oxytocin trial in children with a mouse experiment, keeping study models, administration routes and measured outcomes in context.
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Research Updates
Using FDA and ICH Frameworks to Separate Identity, Purity, and Strength in Peptide Reviews
Use ICH and FDA guidance to separate peptide identity, purity and strength claims, assess validation evidence, and read certificates within their scope.
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Research Updates
MHC-II Profiling Identifies 57 Bacterial Peptides in Mouse Cells
A tularemia study identified 57 MHC-II-associated bacterial peptides in mouse cells, then tested immune responses and protection in mice.
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Research Updates
Peptide-Related Impurities: Separation Before Interpretation
Review model evidence for peptide deletion products and mass-overlapping variants, with clear distinctions between analytical findings and FDA draft guidance.
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Research Updates
Evaluating Early Scientific Literature and Advisory Regulatory Guidance in Peptide Studies
A practical framework for evaluating peptide research updates. Learn to distinguish peer-reviewed studies, preprints, and draft regulatory guidances.
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Research Updates
Pairing Chromatography With Mass Spectrometry to Overcome Peptide Testing Blind Spots
An in vitro study of 23 synthetic peptides demonstrates why mass spectrometry cannot guarantee purity without adequate high-performance liquid chromatography.
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Research Updates
How to Classify Peptide Literature and Connect Published Claims to Actual Study Designs
Learn how to evaluate peptide research by tracing scientific claims to their original evidence. We examine analytical transferability limits and laboratory methodology.
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Research Updates
Evaluating Analytical Testing Claims and True Laboratory Standards Beyond Simple Validation
Learn how to read method validation evidence in analytical research. Examine how laboratories establish accuracy, precision, and robustness for testing methods.
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Research Updates
Significant Shortages in Human Plasma Pharmacokinetic Data for Natural Bioactive Peptides
Learn how to evaluate peptide research by analyzing experimental models, clinical trials, and translational barriers. Explore the limits of preclinical data.
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Research Updates
Ancestral Lactoferrin Peptides Show Enhanced Laboratory Activity Against Drug-Resistant Bacteria
A PLOS Biology study reports that reconstructed ancestral lactoferrin peptides show enhanced laboratory activity against drug-resistant bacterial strains.
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